Go to: Fibromyalgia Subject Criteria / Healthy Sujbect Criteria / Premenstrual Dysphoric Disorder

Fibromyalgia Syndrome

What is Fibromyalgia Syndrome?

Fibromyalgia Syndrome (FMS) is a chronic disorder characterized by widespread muscle pain and fatigue. Fibromyalgia means pain in the muscle, ligaments and tendons - the fibrous tissues in the body. Syndrome means a set of symptoms that occur together. FMS affects 3 to 6 million Americans, and is more common in women than men. Because the pain and symptoms of FMS are not visible, it may be under-diagnosed.

Often those who suffer from fibromyalgia describe generalized aching and soreness in many areas of the body. Certain parts of the body can be more painful and the pain may move around. The pain can vary from day to day. Many people feel worse in the morning with stiffness. The pain may be aggravated by various activities, emotional stress, and environmental stress. Some people may experience only mild discomfort while for others it may be completely disabling. Physical examination usually shows increased pain sensitivity in various locations.

What is the cause of Fibromyalgia?

The exact cause is currently unkown. The onset of FMS may follow an illness like the flu, a traumatic incident like an automobile accident or fall, or severe emotional stress. Abnormal brain chemistry levels may be present in FMS, although the causality of the abnormalities is not well understood. In addition because of the greater prevalence of FMS in women, the role of sex hormones, such as estrogen and progesterone, is of considerable interest. However, at this time, very little is known about how sex hormones may influence pain and other symptoms of FMS

Other Symptoms

Fatigue is a major problem that can fluctuate in severity just like the pain. Over 90% of people with FMS complain of pervasive fatigue and decreased endurance for physical activities. Poor sleep is another common problem reported by many fibromyalgia sufferers.

Other reported symptoms are: morning stiffness, numbness or tingling in the arms or legs, frequent headaches (migraine and tension-type), irritable bowel syndrome, sensitivity to cold temperatures, facial pain such as temporomandibular joint dysfunction, and changes in mood such as depression and anxiety. Some people also report problems in concentration, memory and express a sense of "mental fogginess".

How you can help in understanding the factors that may be linked to FMS

Researchers from the Department of Anesthesiology at the University of Utah are seeking individuals who are interested in participating in our study of "Symptom Monitoring and Sensory Sensitivity" project. The purpose of this research project is to investigate how sensitivity to pain and symptoms vary across time in women with fibromyalgia. We are particularly interested in how sex hormones affects sensory and stress experience in people who have fibromyalgia. The results of this study will help improve our understanding of the relationship between sensory sensitivity, female hormones, and fibromyalgia. Better understanding of the underlying causes and conditions may help us develop optimal intervention options for people suffering from this debilitating pain disorder.

Who is eligible to participate in this study?

Click on one of the following links below to see if you are a candidate to participate in our study.

For women diagnosed with Fibromyalgia

For pain-free healthy women without fibromyalgia

Help break the chain on pain!


Fibromyalgia Syndrome Research
Created by Reiko Mitsunaga, pain.research@hsc.utah.edu
Fibromyalgia Research at University of Utah Pain Research Center

Last modified on April 4, 2002

URL http://www.painresearch.utah.edu/clinical/fibro.htm