Chapter 6 FIG. 2. Central corticopetal noradrenergic transmission in a primate brain (parasagittal view). The cell bodies of neurons that produce norepinephrine appear as black circles. The major projections of these cell bodies are the dorsal noradrenergic bundle (DNB) and the ventral noradrenergic bundle (VNB). Tissue injury signals from spinoreticular pathways excite the pri- marily noradrenergic locus coeruieus (LC), activating the DNB which extends throughout the limbic brain and to neocortex. ME, median eminence; PAG, periaqueductal gray; HB, haben- ula; NSC, nucleus subcoeruleus; LRN, lateral reticular nucleus; NTS, nucleus tractus solitarius; INF, infundibulum; PVN, paraventricular nucleus. Click here to see the graphic at a different resolution