5.3.2 Catheter Placement for Drug Delivery
Temporary spinal or epidural catheter placement is normally undertaken by
specialists trained to recognize possible complications (e.g., opioid-induced
respiratory depression or hypotension or sensorimotor blockade due to local
anesthetic) and able to deal with these promptly and effectively. The need for
dosage titration and coordination of spinal with systemic medications and
nonmedical therapies requires that the catheter be placed within the framework
of multidisciplinary continuing care. Because identical materials and methods
are often used for percutaneous epidural catheter placement for cancer pain and
for acute postoperative pain control, anesthesiologists typically perform these
techniques and their specific followup. Factors to consider are presented in
Table 12. The placement of catheters other than spinal ones, such as for drug
infusion into interpleural or paravertebral areas, is uncommon, and few data,
other than case reports, are available.
Percutaneous electrical stimulation for the relief of otherwise refractory
cancer pain has likewise not yet been evaluated in controlled trials. Case
reports--limited essentially to the percutaneous insertion of spinal cord
electrodes for dorsal column stimulation--tend to focus on details of the
method, to use nonuniform patient selection criteria, and to use heterogeneous
pain assessment methods and followup duration. Not all experience is favorable
(Meglio, Cioni, and Rossi, 1989). Hence, as Miles and colleagues wrote nearly
20 years ago, "At this stage it seems sensible to concentrate effort on
evaluating the method rather than on encouraging widespread and possibly
indiscriminate use of what is an expensive use and relatively unproven
technique" (Miles, Lipton, Hayward, et al., 1974).
Abdominal Pain
Intraspinal drug delivery systems
Figure 5: Pain Management Plan
Introduction (Invasive nonpharmacologic interventions)
Radiation Therapy
Nerve Blocks
Neuraxial Opioid Infusion
Neuroaugmentation
Index